MATERNAL AND NEONATAL C-REACTIVE PROTEIN AFTER INTERVENTIONS DURING DELIVERY
MATERNAL AND NEONATAL C-REACTIVE PROTEIN AFTER INTERVENTIONS DURING DELIVERY
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DOI：
10.3109/00016349309058160
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发表时间：
1993-10-01
影响因子：
4.3
通讯作者：
KOISTINEN, E
中科院分区：
文献类型：
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作者：
KAAPA, P;KOISTINEN, E
为评价产程干预对母婴C反应蛋白(CRP)的影响，我们采用免疫比浊法对238对母婴(179对正常阴道分娩，36对剖宫产，23对负压引产)在产后24小时和72小时进行C反应蛋白检测。在29例无并发症的阴道分娩中，我们还检测了出生后即刻外周血、母血和新生儿血中的C反应蛋白。母亲及其子代的CRP值在出生时很低，但在阴道分娩后的第一天显著上升。剖宫产导致母体C反应蛋白显著升高，但对新生儿值无影响。抽真空分娩的孕妇和新生儿在出生后24小时都会出现一过性的C反应蛋白升高。新生儿C反应蛋白水平与同时抽血评估的浅表出生组织损伤的存在或大小无关。在分娩过程中进行干预后，母亲和婴儿的CRP释放增加可能与不同程度的组织创伤有关，并可能使对感染存在的评估复杂化。
To evaluate the effects of interventions during delivery on the maternal and neonatal C-reactive protein (CRP) we prospectively measured CRP by immunoturbidometry in 238 mother-infant pairs (179 normal vaginal deliveries, 36 cesarean sections and 23 vacuum extractions) at 24 and 72 hours after delivery. We additionally measured CRP in peripheral maternal and neonatal blood immediately after birth in 29 uncomplicated vaginal deliveries. CRP values in the mothers and their offspring were low at birth, but rose significantly during the first day after vaginal delivery. Cesarean section induced a pronounced elevation of maternal CRP, but had no effect on neonatal values. Delivery by vacuum extraction produced a transient elevation of both maternal and neonatal CRP at 24 hours after birth. Neonatal CRP values were not associated with presence or size of superficial birth tissue trauma evaluated simultaneously with blood sampling. Increased CRP release in mothers and their infants after interventions during delivery may be associated with varying degrees of tissue trauma and can complicate assessment of the presence of infection.