A low-grade extraskeletal osteosarcoma
A low-grade extraskeletal osteosarcoma
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DOI：
10.1007/s00256-002-0589-6
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发表时间：
2003-03-01
影响因子：
2.1
通讯作者：
Itoi, E
中科院分区：
文献类型：
--
作者：
Okada, K;Ito, H;Itoi, E
本文报告一位35岁女性左腿低度骨外骨肉瘤的病例。X线片显示病变周围骨化，提示骨化性肌炎。肿瘤以软骨为主，增殖的软骨细胞细胞密度和细胞异型性为轻至中度。周围可见边缘较清晰的骨形成和梭形细胞的增殖，核异型性极小。MIB-1阳性细胞的平均百分率为9.0%。根据这些组织学发现，诊断为低度恶性骨外骨肉瘤。广泛切除后47个月的临床病程平淡无奇。
The case of a 35-year-old woman with low-grade extraskeletal osteosarcoma of the left leg is presented. Radiographs showed peripheral ossification of the lesion, suggesting myositis ossificans. Most of the tumor was composed of cartilage, and the cellularity and cell atypia of the proliferating chondrocytes were mild to moderate. In the periphery, bone formation with a relatively clear margin and proliferation of spindle cells with minimal nuclear atypia were observed. The average percentage of cells positive for MIB-1 was 9.0%. A diagnosis of low-grade extraskeletal osteosarcoma was made on the basis of these histologic findings. The clinical course 47 months after a wide excision was uneventful.