Characterization, thermal stability and sintering of hydroxyapatite powders prepared by different routes
Characterization, thermal stability and sintering of hydroxyapatite powders prepared by different routes
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DOI：
10.1016/j.matchemphys.2005.05.011
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发表时间：
2005-12-15
影响因子：
4.6
通讯作者：
Mostafa, NY
中科院分区：
文献类型：
--
作者：
Mostafa, NY
羟基磷灰石 (HAP) 粉末前体已用作生物医学应用的起始材料，例如合成骨移植材料和硬组织工程支架。考虑到羟基磷灰石的众多应用，研究了三种不同的 HAP 粉末制备途径。两种粉末是在 100 摄氏度下通过化学沉淀反应制备的，一种是通过机械化学反应制备的。使用化学分析、表面积测量、激光衍射、X 射线衍射 (XRD) 和 SEM 对粉末进行表征。 Ca/P 比值从 1.67 变化到 1.58。化学组成、结晶度和团聚特性取决于制备途径。研究了粉末特性对烧结性的影响。尽管热稳定性和烧结开始取决于 Ca/P 比，但最终烧结密度和机械性能取决于团聚特性和粒度分布。采用机械化学途径制备的羟基磷灰石粉末具有纳米级微晶，具有均匀且较小的团聚粒度分布，并且具有黄油烧结性。 (c) 2005 Elsevier B.V. 保留所有权利。
Hydroxyapatite (HAP) powder precursors have been used as starting material for biomedical applications, such as synthetic bone graft materials and scaffold for hard tissue engineering. Considering the numerous applications of hydroxyapatite, three different routes for HAP powders preparations was investigated. Two powders were prepared by chemical precipitation reactions at 100 degrees C and one by mechanochemical reaction. The powders were characterized using chemical analysis, surface area measurements, laser diffraction, X-ray diffraction (XRD) and SEM. The Ca/P ratios were varied from 1.67 to 1.58. The chemical composition, the crystallinity and the agglomeration characters depend on the preparation route. The effect of powder characteristics on the sinterability was investigated. Although, the thermal stability and hence the start of sintering dependents on the Ca/P ratio, the final sintering density and hence the mechanical properties depends on the agglomeration characteristics and the particle size distribution. Hydroxyapatite powder prepared by mechanochemical route have nano-sized crystallites with a uniform smaller agglomerated particle size distribution and have a butter sinterability. (c) 2005 Elsevier B.V. All rights reserved.