Continuous rocuronium administration for tracheomalacia
Continuous rocuronium administration for tracheomalacia
复制标题
持续给予罗库溴铵治疗气管软化症
DOI：
10.1007/s00540-015-2055-3
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发表时间：
2015
影响因子：
2.8
通讯作者：
Isao Tsuneyoshi
中科院分区：
文献类型：
--
作者：
Teshishi Yano;Masahiko Taniguchi;Isao Tsuneyoshi
增加儿童呼吸努力的活动可能会加剧症状，包括咳嗽和哭泣，这会增加胸内压，直到腔外压力超过腔内压力，气管塌陷[1]。如我们的病例所示，通过减少咳嗽和哭泣时由于肋间和腹肌收缩引起的胸腔内压升高，可以预防低血压发作。总之，我们建议对机械通气患者使用罗库溴铵作为预防严重气管软化导致的危及生命的缺氧发作的药理支持。
Symptoms may be exacerbated by activities that increase a child’s respiratory efforts, including coughing and crying, which can increase intrathoracic pressure until the extraluminal pressure exceeds the intraluminal pressure, and the trachea collapses [1]. Hypoxic episodes might be prevented by reducing the increase of intrathoracic pressure due to intercostal and abdominal muscle contraction during coughing and crying, as in our cases. In conclusion, we recommend using rocuronium for ventilated patients as a pharmacological support for the prevention of life-threatening hypoxic episodes due to severe tracheomalacia.