Non-linear inverse scattering: High resolution quantitative breast tissue tomography
Non-linear inverse scattering: High resolution quantitative breast tissue tomography
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DOI：
10.1121/1.3699240
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发表时间：
2012-05-01
影响因子：
2.4
通讯作者：
Berggren, M.
中科院分区：
文献类型：
--
作者：
Wiskin, J.;Borup, D. T.;Berggren, M.
最近公布的逆散射结果通常表明，当采用线性化或迭代线性化算法（例如，扭曲Born迭代法）。本文提出了一种完全非线性算法，利用全波场数据，结果在超声计算机断层扫描图像从实验室乳腺扫描仪，并显示了几个这样的独特的图像从志愿者受试者。讨论了正问题、数据采集过程和所用的逆散射算法。表示预测数据和测量数据之间的“最佳拟合”的泛函被最小化，因此需要非常快速的向前问题求解器、雅可比计算和梯度估计，所有这些都被描述。描述了数据采集装置。该算法和设备产生人体乳腺组织在体内的定量估计。几个高分辨率的图像，测量类似于150 150波长，从二维逆散射算法，使用从第一原型收集的数据，显示和讨论。定量值与以前发表的工作进行了比较。(C)2012年美国声学学会。[http：//dx.doi.org/10.1121/1.3699240]
Recent published results in inverse scattering generally show the difficulty in dealing with moderate to high contrast inhomogeneities when employing linearized or iteratively linearized algorithms (e.g., distorted Born iterative method). This paper presents a fully nonlinear algorithm utilizing full wave field data, that results in ultrasound computed tomographic images from a laboratory breast scanner, and shows several such unique images from volunteer subjects. The forward problem, data collection process and inverse scattering algorithm used are discussed. A functional that represents the "best fit" between predicted and measured data is minimized, and therefore requires a very fast forward problem solver, Jacobian calculation, and gradient estimation, all of which are described. The data collection device is described. The algorithm and device yield quantitative estimates of human breast tissue in vivo. Several high resolution images, measuring similar to 150 by 150 wavelengths, obtained from the 2D inverse scattering algorithms, using data collected from a first prototype, are shown and discussed. The quantitative values are compared with previous published work. (C) 2012 Acoustical Society of America. [http://dx.doi.org/10.1121/1.3699240]