TOTAL LUNG CAPACITY MEASURED BY BODY PLETHYSMOGRAPHY AND BY THE HELIUM DILUTION METHOD - A COMPARATIVE-STUDY IN DIFFERENT PATIENT GROUPS
TOTAL LUNG CAPACITY MEASURED BY BODY PLETHYSMOGRAPHY AND BY THE HELIUM DILUTION METHOD - A COMPARATIVE-STUDY IN DIFFERENT PATIENT GROUPS
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DOI：
10.1111/j.1475-097x.1988.tb00199.x
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发表时间：
1988-04-01
期刊：
影响因子：
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通讯作者：
WALKER, A
中科院分区：
文献类型：
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作者：
ANDERSSON, LG;RINGQVIST, I;WALKER, A
众所周知，氦气稀释法会低估肺部通气不良或无通气区域患者的总肺容量（TLC）。据报道，标准体积描记法高估了严重气道阻塞患者的TLC。为了确定两种方法之间的差异程度，在不同的患者组中进行了比较。在一组正常的肺功能测试（n = 20）的患者中，体积描记法和氦稀释法之间的TLC有一个小的，但显着的平均差异，后者获得的值较大。在中度气道阻塞（n = 23）、重度气道阻塞（n = 20）或肺气肿（n = 19）的患者组中，平均差异不显著，尽管肺气肿组中有2例患者的体积描记值显著大于氦稀释法获得的值。我们的结论是，气体稀释法和体积描记法与压力补偿容积置换体积描记器的TLC的估计，同意即使在患者的气道阻塞或肺气肿，除了在非常严重的肺部疾病的患者。
The helium dilution method is known to underestimate the total lung capacity (TLC) in patients with poorly or non-ventilated areas in the lungs. The standard plethysmographic method has been reported to overestimate TLC in patients with severe airway obstruction. To determine the magnitude of the difference between the two methods, a comparison was made in differnt patients groups. In a group of patients with normal lung function tests (n = 20) there was a small but significant average difference in TLC between plethysmography and the helium dilution method, the larger values being obtained with the latter. In patient groups with moderately obstructed airways (n = 23), severely obstructed airways (n = 20), or emphysema (n = 19), there were no significant average differences, although in two patients in the emphysema group the plethysmorgaphic values were considerably larger than those obtained by helium dilution. We conclude that the gas dilution methods and plethysmography with a pressure-compensated volume displacement plethysmograph gave estimates of TLC which agreed even in patients with airway obstruction or emphysema, except in patients with very severe lung disease.