THE NATURE AND COURSE OF DEPRESSION FOLLOWING MYOCARDIAL-INFARCTION
THE NATURE AND COURSE OF DEPRESSION FOLLOWING MYOCARDIAL-INFARCTION
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DOI：
10.1001/archinte.149.8.1785
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发表时间：
1989-08-01
影响因子：
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通讯作者：
ZUCKER, HD
中科院分区：
文献类型：
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作者：
SCHLEIFER, SJ;MACARIHINSON, MM;ZUCKER, HD
对两所城市教学医院的283名因心肌梗死而住进心脏监护室的患者在发病后8~10天进行访谈，并在3~4个月后再次访谈。最初，45%的人符合轻度或重度抑郁症的诊断标准，其中18%的人患有重度抑郁综合征。抑郁与心脏疾病的严重程度无关，但与非心脏内科疾病的存在有关。梗死后3至4个月，33%的患者符合轻度或重度抑郁症的标准。大多数最初符合重度但不是轻度抑郁症标准的患者在3个月后表现出抑郁的迹象，大多数患有重度抑郁症的患者在3个月后仍未重返工作岗位。治疗心肌梗死后的主要抑郁综合征可能会减少慢性化和残疾，而轻微的抑郁综合征可能类似于正常的悲痛，并倾向于自我限制。
Two hundred eighty-three patients admitted to cardiac care units for myocardial infarction at two urban teaching hospitals were interviewed 8 to 10 days after infarction and 171 were reinterviewed 3 to 4 months later. Initially, 45% met diagnostic criteria for minor or major depression, including 18% with major depressive syndromes. Depression was not associated with the severity of cardiac illness but was associated with the presence of noncardiac medical illnesses. Three to 4 months after infarction, 33% of patients met criteria for minor or major depression. The large majority of patients who initially met criteria for major but not minor depression showed evidence of depression at 3 months and most patients with major depression had not returned to work by 3 months. Treatment of major depressive syndromes after myocardial infarction may reduce chronicity and disability, while minor depressive syndromes may be similar to normal grief and tend to be self-limited.