White rice consumption and risk of type 2 diabetes: meta-analysis and systematic review.
White rice consumption and risk of type 2 diabetes: meta-analysis and systematic review.
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DOI：
10.1136/bmj.e1454
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发表时间：
2012-03-15
期刊：
影响因子：
--
通讯作者：
Sun Q
中科院分区：
文献类型：
--
作者：
Hu EA;Pan A;Malik V;Sun Q
目的总结白米摄入量与2型糖尿病风险之间关系的证据，并量化其潜在的剂量-反应关系。设计前瞻性队列研究的Meta分析。数据来源：在Medline和Embase数据库中检索截至2012年1月发表的文章，检索的关键词包括大米摄入量和糖尿病；进一步搜索参考文献包括原始研究。研究选择包括前瞻性队列研究，报告了大米摄入量对2型糖尿病风险的估计。数据综合使用随机效应模型合并相对风险；使用每项研究中所有大米摄入量类别的数据评估剂量-反应关系。结果本研究共确定了4篇文章，包括7篇针对亚洲和西方人群的不同前瞻性队列分析。在352名 384名参与者中，共确诊了13例 284例2型糖尿病事件，随访期为4至22年。亚洲(中国和日本)人群的白米消费水平远高于西方人群(平均摄入量为每天三至四份，而不是每周一至两份)。在亚洲人群中，白米摄入量最高和最低类别的合并相对危险度为1.5 5(95%可信区间1.2 0~2.0 1)，而在西方人群中，相对危险度为1.12(0.94~1.3 3)(交互作用P=0.038)。在总体人群中，剂量-反应Meta分析表明，白米摄入量每增加一份，患2型糖尿病的相对危险度为1.11(1.08~1.14)(P=线性趋势&t；0.001)。结论高白米摄入量与2型糖尿病发病风险显著相关，尤其是在亚洲(中国和日本)人群中。
Objectives To summarise evidence on the association between white rice consumption and risk of type 2 diabetes and to quantify the potential dose-response relation. Design Meta-analysis of prospective cohort studies. Data sources Searches of Medline and Embase databases for articles published up to January 2012 using keywords that included both rice intake and diabetes; further searches of references of included original studies. Study selection Included studies were prospective cohort studies that reported risk estimates for type 2 diabetes by rice intake levels. Data synthesis Relative risks were pooled using a random effects model; dose-response relations were evaluated using data from all rice intake categories in each study. Results Four articles were identified that included seven distinct prospective cohort analyses in Asian and Western populations for this study. A total of 13 284 incident cases of type 2 diabetes were ascertained among 352 384 participants with follow-up periods ranging from 4 to 22 years. Asian (Chinese and Japanese) populations had much higher white rice consumption levels than did Western populations (average intake levels were three to four servings/day versus one to two servings/week). The pooled relative risk was 1.55 (95% confidence interval 1.20 to 2.01) comparing the highest with the lowest category of white rice intake in Asian populations, whereas the corresponding relative risk was 1.12 (0.94 to 1.33) in Western populations (P for interaction=0.038). In the total population, the dose-response meta-analysis indicated that for each serving per day increment of white rice intake, the relative risk of type 2 diabetes was 1.11 (1.08 to 1.14) (P for linear trend<0.001). Conclusion Higher consumption of white rice is associated with a significantly increased risk of type 2 diabetes, especially in Asian (Chinese and Japanese) populations.
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影响因子：
5
作者：
GREENLAND, S;LONGNECKER, MP
通讯作者：
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影响因子：
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作者：
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DOI：
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