The African swine fever virus IAP homolog is a late structural polypeptide

The African swine fever virus IAP homolog is a late structural polypeptide
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DOI:
10.1006/viro.1995.0083
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发表时间:
1995-12-20
期刊:
影响因子:
3.7
通讯作者:
Rodriguez, JF
Rodriguez, JF
中科院分区:
医学3区
文献类型:
--
作者:
Chacon, MR;Almazan, F;Rodriguez, JF

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d对非洲猪瘟病毒基因组完整核苷酸序列的分析表明,存在着一些可能能够改变宿主对病毒感染的反应的基因。在这份报告中,我们描述了A224L基因的特性的结果,该基因编码一个新的成员称为IAP蛋白的凋亡抑制剂的家庭。A224L在感染周期的晚期表达,其多肽产物组装成病毒颗粒。(C)出版社:Academic Press
dThe analysis of the complete nucleotide sequence of the African swine fever virus genome has revealed the existence of a number of genes potentially capable of modifying the host's response to the virus infection. In this report, we describe the results of the characterization of the A224L gene that encodes a novel member of the family of apoptosis inhibitors known as IAP proteins. A224L is expressed during the late phase of the infectious cycle, and its polypeptide product is assembled into virus particles. (C) 1995 Academic Press, Inc.