Inducing and Evaluating Skeletal Muscle Injury by Notexin and Barium Chloride.

Inducing and Evaluating Skeletal Muscle Injury by Notexin and Barium Chloride.
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DOI:
10.1007/978-1-4939-3810-0_5
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发表时间:
2016
影响因子:
--
通讯作者:
Matthew T. Tierney;A. Sacco
Matthew T. Tierney;A. Sacco
中科院分区:
--
文献类型:
--
作者:
Matthew T. Tierney;A. Sacco

文献摘要

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动物模型中的骨骼肌损伤模型是评估肌肉干细胞(MuSC)介导的组织修复的宝贵工具。这些方法的优化和综合评估大大提高了我们评估MuSC再生潜力的能力。在这里,我们描述的程序与notexin和氯化钡骨骼肌损伤和评估的动态组织再生。
Models of skeletal muscle injury in animal models are invaluable tools to assess muscle stem cell (MuSC)-mediated tissue repair. The optimization and comprehensive evaluation of these approaches have greatly improved our ability to assess MuSC regenerative potential. Here we describe the procedures for skeletal muscle injury with notexin and BaCl2and assessment of the dynamics of tissue regeneration.