Sex-specific associations of magnetic resonance imaging-derived intra-abdominal and subcutaneous fat areas with conventional anthropometric indices - The atherosclerosis risk in communities
Sex-specific associations of magnetic resonance imaging-derived intra-abdominal and subcutaneous fat areas with conventional anthropometric indices - The atherosclerosis risk in communities
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DOI：
10.1093/oxfordjournals.aje.a008934
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发表时间：
1996-08-15
影响因子：
5
通讯作者：
Heiss, G
中科院分区：
文献类型：
--
作者：
Schreiner, PJ;Terry, JG;Heiss, G
通过传统的人体测量法难以获得中心脂肪图案的精确测量。通过磁共振成像直接测量腹内脂肪面积虽然准确，但对于大规模观察性研究来说是不切实际的。本报告探讨了性别特异性协会的传统人体测量指数与腹内脂肪和皮下脂肪面积的磁共振成像测量。共有157名志愿者（97名男性和60名女性），年龄48-68岁，主要是白色种族，作为社区动脉粥样硬化风险（ARIC）研究的一部分，测量了腹内脂肪和皮下脂肪面积。体重、体重指数、腰围、腰臀比和肩胛下皮褶厚度通过标准化方案测量或计算。平均而言，女性的腹内脂肪面积低于男性（109.5 cm（2）vs. 152.9 cm（2）），但平均皮下脂肪面积高于男性（287.8 cm（2）vs. 214.6 cm（2））。在调整年龄后，男性腹内脂肪面积与体重指数、腰围、体重和肩胛下皮褶厚度呈二次相关;在女性中，这些相关性最好用正线性方程建模。在两种性别中，腰臀比与腹内脂肪面积呈线性相关。在一般情况下，人体测量的措施预测的百分比较低的总方差在腹内脂肪面积的男性比女性。对于皮下脂肪面积，所有人体测量指标线性相关，并预测更多的变异，皮下脂肪面积比腹内脂肪面积。这些结果表明，在男性中，相对较低的体重会产生更大的腹内脂肪沉积率，而体重较高时脂肪沉积更均匀。女性体重增加时，腹部脂肪似乎以恒定的速度存款，即使在绝经后也是如此。作者得出结论，当腰围或体重指数被用作男性腹内脂肪面积的替代物时，应在分析中包括二次项作为预测变量，皮下脂肪面积可以通过流行病学研究中常用的线性测量来很好地估计。
Accurate measurement of central fat patterning is difficult to obtain by conventional anthropometry. Direct measurement of intra-abdominal fat area by magnetic resonance imaging, while accurate, is impractical for large-scale observational studies. This report examines the sex-specific associations of conventional anthropometric indices with intra-abdominal fat and subcutaneous fat areas measured by magnetic resonance imaging. A total of 157 volunteers (97 men and 60 women) aged 48-68 years of predominately white ethnicity had intra-abdominal fat and subcutaneous fat areas measured as part of the Atherosclerosis Risk in Communities (ARIC) Study. Weight, body mass index, waist circumference, waist:hip ratio, and subscapular skinfold thickness were measured or calculated by a standardized protocol. On average, women had a lower intra-abdominal fat area than men (109.5 cm(2) vs. 152.9 cm(2)) but a higher mean subcutaneous fat area (287.8 cm(2) vs. 214.6 cm(2)). After adjustment for age,intra-abdominal fat area was quadratically associated with body mass index, waist circumference, weight, and subscapular skinfold thickness in men; in women, these associations were best modeled by a positive linear equation. Waist:hip ratio was linearly related to intraabdominal fat area in both sexes. In general, anthropometric measures predicted lower percentages of the total variance in intra-abdominal fat area for men than for women. For subcutaneous fat area, all anthropometric indices were linearly associated and predicted more of the variance in subcutaneous fat area than in intra-abdominal fat area. These results indicate that among men, greater intra-abdominal fat deposition rates occur at relatively low body weights and fat is more uniformly deposited at higher weights. Women appear to deposit intra-abdominal fat at a constant rate as they gain weight, even after menopause. The authors conclude that when waist circumference or body mass index is used as a surrogate for intra-abdominal fat area in men, a quadratic term should be included in the analysis as a predictor variable, Subcutaneous fat area can be estimated well by linear measures commonly employed in epidemiologic studies.