The biological perspective on mother-infant bonding: the importance of oxytocin
The biological perspective on mother-infant bonding: the importance of oxytocin
复制标题
DOI：
10.2502/janip.63.1.4
复制
发表时间：
2013
期刊：
影响因子：
--
通讯作者：
M. Nagasawa;Shota Okabe;K. Mogi;T. Kikusui
中科院分区：
文献类型：
--
作者：
M. Nagasawa;Shota Okabe;K. Mogi;T. Kikusui
这篇综述显示了催产素在啮齿动物中参与纽带形成的作用以及导致母婴纽带的相互沟通方式。各种社会刺激，例如从幼崽到母亲的触觉刺激和超声波发声（USV），以及从母亲到幼崽的喂养和触觉刺激，增强了大鼠和小鼠的母婴关系形成。这表明母亲和婴儿能够发展出彼此的跨模式感官识别。尽管婴儿大脑中形成纽带的机制尚未阐明，但神经系统中的催产素在母婴纽带过程的各个方面都发挥着关键作用。母亲社会刺激的剥夺强烈影响后代的社会性，包括母亲对自己后代的行为，这意味着“母亲环境的非基因组传递”。对母亲和婴儿之间的认知功能以及母婴关系所涉及的生物学机制的比较理解可能有助于我们理解与母婴关系相关的精神疾病。
This review shows the effects of oxytocin involved in bond formation and the manner of reciprocal communication leading to mother-infant bonding in rodents. Various social stimuli, such as tactile stimuli and ultrasonic vocalizations (USVs) from the pups to the mother, and feeding and tactile stimulation from the mother to the pups, reinforce the motherinfant bond formation in rats and mice. This suggests that the mother and infant are able to develop a cross-modal sensory recognition of each other. Although the mechanisms underlying bond formation in the brains of infants have not yet been clarified, oxytocin in the neural system plays a pivotal role in each sides of the mother-infant bonding process. The deprivation of social stimuli from the mother strongly influences the offspring’s sociality, including maternal behavior towards their own offspring, which implies the “non-genomic transmission of maternal environment.” The comparative understanding of cognitive functions between mother and infants, and the biological mechanisms involved in mother-infant bonding may help us understand psychiatric disorders associated with mother-infant relationships.