Estrogen receptor β:: Re-evaluation of estrogen and antiestrogen signaling
Estrogen receptor β:: Re-evaluation of estrogen and antiestrogen signaling
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DOI：
10.1016/s0039-128x(98)00024-5
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发表时间：
1998-05-01
期刊：
影响因子：
2.7
通讯作者：
Tremblay, GB
中科院分区：
文献类型：
--
作者：
Giguère, V;Tremblay, A;Tremblay, GB
雌激素对生殖功能的发育和控制至关重要。直到最近，人们还认为雌激素通过与属于配体依赖性转录因子超家族的独特核受体结合来调节基因表达的复杂程序。然而，第二种雌激素受体（称为ERP）的鉴定导致了对雌激素信号传导和生理学的重新评估。(C)1998年，Elsevier Science Inc.
Estrogen is of vital importance for the development and control of reproductive functions. Until recently, estrogen was believed to regulate complex programs of gene expression by binding to an unique nuclear receptor belonging to the superfamily of ligand-dependent transcription factors. However, the identification of a second estrogen receptor, referred to as ERP, is leading to a re-evaluation of estrogen signaling and physiology. (C) 1998 by Elsevier Science Inc.