The epidemiology of venous thromboembolism
The epidemiology of venous thromboembolism
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DOI：
10.1007/s11239-015-1311-6
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发表时间：
2016-01-01
影响因子：
4
通讯作者：
White, Richard H.
中科院分区：
文献类型：
--
作者：
Heit, John A.;Spencer, Frederick A.;White, Richard H.
静脉血栓栓塞（VTE）被美国外科医生归类为一个主要的公共卫生问题。静脉血栓栓塞相对常见，与生存率降低和大量医疗保健费用有关，并且经常复发。静脉血栓栓塞是一种复杂（多因素）疾病，涉及血栓形成的获得性或遗传性易感性与静脉血栓栓塞风险因素之间的相互作用，包括患者年龄增加和肥胖、因手术或急性疾病住院、疗养院限制、活动性癌症、创伤或骨折、不动或下肢轻瘫、浅静脉血栓形成，以及女性妊娠和产褥期、口服避孕药和激素治疗。尽管独立的VTE风险因素和VTE复发的预测因素已经确定，并且有效的一级和二级预防是可用的，但VTE的发生似乎相对恒定，甚至增加。
Venous thromboembolism (VTE) is categorized by the U.S. Surgeon General as a major public health problem. VTE is relatively common and associated with reduced survival and substantial health-care costs, and recurs frequently. VTE is a complex (multifactorial) disease, involving interactions between acquired or inherited predispositions to thrombosis and VTE risk factors, including increasing patient age and obesity, hospitalization for surgery or acute illness, nursing-home confinement, active cancer, trauma or fracture, immobility or leg paresis, superficial vein thrombosis, and, in women, pregnancy and puerperium, oral contraception, and hormone therapy. Although independent VTE risk factors and predictors of VTE recurrence have been identified, and effective primary and secondary prophylaxis is available, the occurrence of VTE seems to be relatively constant, or even increasing.