P300 as a clinical assay: rationale, evaluation, and findings
P300 as a clinical assay: rationale, evaluation, and findings
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DOI：
10.1016/s0167-8760(00)00127-6
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发表时间：
2000-10-01
影响因子：
3
通讯作者：
Herbst, KL
中科院分区：
文献类型：
--
作者：
Polich, J;Herbst, KL
使用P300事件相关脑电位（ERP）作为一种临床试验进行审查和评估，通过比较其分布质量与规范的生物医学测试数据从已发表的研究。计算P300数据和各种临床测试数据的变异系数统计量。P300振幅和潜伏期的变异性被认为是高度可比的，有时上级常规采用的生物医学测定。这些结果进行了讨论，在如何控制组间ERP的变异性和规范的P300数据在临床环境中的应用。(C)2000 Elsevier Science B.V.保留所有权利。
Use of the P300 event-related brain potential (ERP) as a clinical assay is reviewed and assessed by comparing its distribution qualities with normative biomedical testing data from published studies. The coefficient of variation statistic was calculated for P300 data and a variety of clinical testing data. P300 amplitude and latency variability was found to be highly comparable and sometimes superior to routinely employed biomedical assays. These results are discussed in terms of how to control inter-group ERP variability and the application of normative P300 data in clinical settings. (C) 2000 Elsevier Science B.V. All rights reserved.