Prenatal alcohol exposure alters adult expression of sexually dimorphic behavior in the rat.
Prenatal alcohol exposure alters adult expression of sexually dimorphic behavior in the rat.
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产前酒精暴露会改变大鼠成年后性别二态行为的表达。
DOI：
10.1126/science.6719121
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发表时间：
1984
期刊：
影响因子：
56.9
通讯作者：
E. Noble
中科院分区：
文献类型：
--
作者：
R. McGivern;A. Clancy;M. A. Hill;E. Noble
研究发现，在妊娠期暴露于酒精的成年雄性和雌性大鼠中，Lashley III迷宫中的Escherin偏好和表现发生了改变。具体而言，通常在这两种行为中观察到的性别二型性在胎儿酒精暴露的动物中不存在。缺乏性二态性似乎是由于暴露的女性男性化和暴露的男性女性化。
Saccharin preference and performance in a Lashley III maze were found to be altered in adult male and female rats that had been exposed to alcohol during gestation. Specifically, the sexual dimorphism normally observed in both behaviors was absent in fetal alcohol-exposed animals. The lack of sexual dimorphism appeared to result from a masculinization of the exposed females and a feminization of the exposed males.