Optically active β-ketoiminato cobalt(II) complexes as highly efficient catalysts in enantioselective borohydride reduction of ketones, imines, and α,β-unsaturated carboxylates
Optically active β-ketoiminato cobalt(II) complexes as highly efficient catalysts in enantioselective borohydride reduction of ketones, imines, and α,β-unsaturated carboxylates
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光学活性 β-酮亚胺钴 (II) 配合物作为酮、亚胺和 α,β-不饱和羧酸酯对映选择性硼氢化物还原的高效催化剂
DOI：
10.1016/s0020-1693(99)00373-4
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发表时间：
1999
影响因子：
2.8
通讯作者：
T. Mukaiyama
中科院分区：
文献类型：
--
作者：
T. Yamada;T. Nagata;T. Ikeno*;Y. Ohtsuka;A. Sagara;T. Mukaiyama
合成了一类新的具有光学活性的N，N′-亚乙基双酮亚胺配体的钴配合物，并对其中一个配合物进行了X-射线晶体学分析。这些钴（II）配合物被证明是对映选择性硼氢化还原芳基酮、膦基亚胺和β，β-二取代α，β-不饱和羧酸酯的有效催化剂。结果表明，钴配合物催化剂的二苯基乙二胺结构对硼氢化物还原反应的对映体选择性有影响。
A new class of cobalt complexes with optically active N,N′-ethylenebisketoiminato ligands was synthesized, and one of them was fully characterized by X-ray crystallographic analysis. These cobalt(II) complexes proved to be efficient catalysts in enantioselective borohydride reduction of aryl ketones, phosphinyl imines, and β,β-disubstituted α,β-unsaturated carboxylates. It was found that the enantiofacial discrimination in the borohydride reduction was influenced by the structure of the diphenylethylenediamine moiety of the cobalt complex catalysts.