Effects of nutritional status on hormone concentrations of the somatotropin axis and metabolites in plasma and colostrum of Japanese Black cows
Effects of nutritional status on hormone concentrations of the somatotropin axis and metabolites in plasma and colostrum of Japanese Black cows
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DOI：
10.1111/asj.12686
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发表时间：
2017-04-01
影响因子：
2
通讯作者：
Gotoh, Takafumi
中科院分区：
文献类型：
--
作者：
Phomvisith, Ouanh;Takahashi, Hideyuki;Gotoh, Takafumi
本研究旨在探讨不同营养状况对产前晚期奶牛血浆和初乳中生长激素(GH)和胰岛素样生长因子-1(IGF-1)、胰岛素及其代谢物(葡萄糖、总蛋白和非酯化脂肪酸)浓度的影响。将8头妊娠日本黑牛随机分为2个试验组，每组4头。对照奶牛(CON)在分娩前获得100%的营养需求，而限制组奶牛(RES)获得60%的营养需求。产前采血，产后第0、1、3天采血和初乳。与CON组相比，RES组大鼠血浆GH和NEFA浓度明显升高，而血糖和胰岛素浓度显著降低。RES奶牛产后血浆GH浓度显著高于CON奶牛，而血浆总蛋白显著低于CON奶牛。与CON组相比，RES组初乳中GH浓度显著升高，而蛋白质总浓度显著降低。两组患者血清IGF-1浓度差异无统计学意义。这些发现表明，妊娠晚期母牛的营养状况会影响日本黑牛血液和初乳中生长激素和总蛋白的浓度。
We aimed to determine the effects of nutritional status on concentrations of somatotropic axis hormones (growth hormone (GH) and insulin-like growth factor 1 (IGF-1)), insulin and metabolites (glucose, total protein and nonesterified fatty acids (NEFA)) in the plasma and colostrum in late antepartum cows. Eight pregnant Japanese Black cows were randomly assigned to two experimental groups (n=4 per group). Control cows (CON) received 100% of their nutritional requirements until parturition, whereas restricted group cows (RES) received 60% of their nutritional requirements. Blood samples were taken during the antepartum period, and blood and colostrum samples were collected on days 0, 1, and 3 after calving. Compared to the CON group, the RES group had higher concentrations of GH and NEFA in plasma, but significantly lower concentrations of glucose and insulin in plasma. The concentrations of GH in plasma after calving were significantly higher, but total plasma protein was significantly lower in RES than in CON cows. Compared to the CON group, the RES group had significantly higher concentrations of GH in colostrum, but significantly lower total concentrations of protein in colostrum. Concentrations of IGF-1 were not different between the two groups. These findings suggest that maternal nutritional status during late gestation influences concentrations of GH and total protein in the blood and colostrum of Japanese Black cows.