Re-excision rates after breast conserving surgery following the 2014 SSO-ASTRO guidelines

Re-excision rates after breast conserving surgery following the 2014 SSO-ASTRO guidelines
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DOI:
10.1016/j.amjsurg.2017.08.023
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发表时间:
2017-12-01
影响因子:
3
通讯作者:
Murphy, Colleen
Murphy, Colleen
中科院分区:
医学3区
文献类型:
--
作者:
Gladden, Alicia A. Heelan;Sams, Sharon;Murphy, Colleen

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背景:2014 年,SSO-ASTRO 发布了指南,建议“肿瘤上无墨水”作为接受浸润性乳腺癌患者保乳的足够边缘。 2016 年,新的 SSO-ASTRO-ASCO 指南建议 DCIS 的边缘为 2 毫米。我们评估了这些指南是否影响我们机构的再切除率。方法:确定了 2010 年 1 月 1 日至 2016 年 3 月 1 日期间接受保乳手术的患者。记录再切除率、肿瘤特征和残留病灶的存在。回顾性地将2016年指南应用于同一队列,并计算预期的再切除率。结果:在2014年指南采用之前和之后(之前11.9%,之后10.9%;p = 0.65)或回顾性应用2016年指南时(8.4%;p = 0.10),再切除率没有显着下降。结论:2014年和2016年指南对我们的再切除率影响很小,因为大多数再切除是针对 DCIS 进行的,并且 2016 年指南支持我们之前对这些患者采用 2 毫米切缘的机构实践。 (C) 2017 Elsevier Inc. 保留所有权利。
Background: In 2014, SSO-ASTRO published guidelines which recommended "no ink on tumor" as adequate margins for patients undergoing breast conservation for invasive breast cancer. In 2016, new SSO-ASTRO-ASCO guidelines recommended 2 mm margins for DCIS. We evaluated whether these guidelines affected re-excision rates at our institution.Methods: Patients treated with breast conservation surgery from January 1, 2010-March 1, 2016 were identified. Re-excision rates, tumor characteristics, and presence of residual disease were recorded. The 2016 guidelines were retrospectively applied to the same cohort and expected re-excision rates calculated.Results: Re-excision rates did not significantly decline before and after 2014 guideline adoption (11.9% before, 10.9% after; p = 0.65) or when the 2016 guidelines were retrospectively applied (8.4%; p = 0.10).Conclusions: The 2014 and 2016 guidelines had minimal impact on our re-excision rates, as most re-excisions were done for DCIS and 2016 guidelines supported our prior institutional practices of 2 mm margins for these patients. (C) 2017 Elsevier Inc. All rights reserved.