Influence of exercise on ascorbic acid status in man.
Influence of exercise on ascorbic acid status in man.
复制标题
运动对人类抗坏血酸状态的影响。
DOI：
10.1042/cs0730501
复制
发表时间：
1987
期刊：
影响因子：
6
通讯作者：
R. Maughan
中科院分区：
文献类型：
--
作者：
M. Gleeson;J. Robertson;R. Maughan
1. 本文研究了9名参加21公里赛跑的男子血液循环白细胞对粒细胞和淋巴细胞数量、比例以及血浆和分离淋巴细胞抗坏血酸（AA）浓度变化的反应。比赛后5分钟出现明显的白细胞增多，主要增加的是粒细胞（P < 0.001），而循环淋巴细胞（P < 0.01）和血小板（P < 0.001）的相对增加较小。白细胞和血小板在比赛后24小时内恢复到运动前的水平。2. 血浆AA浓度从赛前的52.7 +/- 4.1 mumol/l上升到赛后5min内的67.0 +/- 5.3 mumol/l （P < 0.001）。血浆AA浓度升高与比赛期间血浆皮质醇浓度升高呈显著正相关（r = 0.89, P < 0.01）。然而，在比赛后24 h内，血浆AA浓度比运动前下降了20 +/- 4% (P < 0.01)，并在接下来的至少2天内保持在低水平（P < 0.05）。3. 比赛期间淋巴细胞AA浓度由15.6 +/- 0.6 μ mol/g升高至19.7 +/- 0.9 μ mol/g (P < 0.01)，赛后2 d内恢复正常。4. 提示肾上腺可能是运动时AA外排进入循环的主要来源。
1. The response of circulating leucocytes with regard to changes in number, proportion of granulocytes and lymphocytes, as well as changes in the ascorbic acid (AA) concentration of plasma and isolated lymphocytes, were studied in nine men who ran a 21 km race. A marked leucocytosis was noted 5 min after the race, the predominant increase being in granulocytes (P less than 0.001) with smaller relative increases in circulating lymphocytes (P less than 0.01) and platelets (P less than 0.001). Numbers of leucocytes and platelets returned to pre-exercise levels within 24 h after the race. 2. The concentration of AA in plasma increased from 52.7 +/- 4.1 mumol/l before the race to 67.0 +/- 5.3 mumol/l within 5 min after the race (P less than 0.001). This increase in plasma AA concentration was positively correlated with the rise in plasma cortisol concentration during the race (r = 0.89; P less than 0.01). However, within 24 h after the race the plasma concentration of AA fell 20 +/- 4% below pre-exercise values (P less than 0.01) and remained low for at least the next 2 days (P less than 0.05). 3. Lymphocyte AA concentration increased from 15.6 +/- 0.6 to 19.7 +/- 0.9 mumol/g of lymphocyte protein during the race (P less than 0.01) but returned to normal levels within 2 days after the race. 4. It is suggested that the adrenal gland may be the major source of AA efflux into the circulation during exercise.