Long-term comparison of 3 controller regimens for mild-moderate persistent childhood asthma: The Pediatric Asthma Controller Trial
Long-term comparison of 3 controller regimens for mild-moderate persistent childhood asthma: The Pediatric Asthma Controller Trial
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DOI：
10.1016/j.jaci.2006.09.042
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发表时间：
2007-01-01
影响因子：
14.2
通讯作者：
Taussig, Lynn M.
中科院分区：
文献类型：
--
作者：
Sorkness, Christine A.;Lemanske, Robert F., Jr.;Taussig, Lynn M.
背景：需要更多的证据来作为治疗学龄儿童轻中度持续性哮喘的建议的基础。目的：儿科哮喘控制试验（PACT）比较3种方案在实现哮喘控制方面的有效性。方法：285例根据症状诊断为轻中度持续性哮喘的儿童（6-14岁），FEV1 >= 80%预测，甲胆碱FEV1 PC20 = 80%预测，确认现行指南建议。
Background: More evidence is needed on which to base recommendations for treatment of mild-moderate persistent asthma in school-aged children.Objective: The Pediatric Asthma Controller Trial (PACT) compared the effectiveness of 3 regimens in achieving asthma control.Methods: A total of 285 children (ages 6-14 years) with mild-moderate persistent asthma on the basis of symptoms, and with FEV1 >= 80% predicted and methacholine FEV1 PC20 = 80% predicted, confirming current guideline recommendations.