Next-Generation Digital Information Storage in DNA
Next-Generation Digital Information Storage in DNA
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DOI：
10.1126/science.1226355
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发表时间：
2012-09-28
期刊：
影响因子：
56.9
通讯作者：
Kosuri, Sriram
中科院分区：
文献类型：
--
作者：
Church, George M.;Gao, Yuan;Kosuri, Sriram
数字信息正以惊人的速度积累，使我们存储和存档的能力变得紧张。DNA是已知的最密集和最稳定的信息媒介之一。DNA合成和测序新技术的发展使DNA成为越来越可行的数字存储介质。我们开发了一种在DNA中编码任意数字信息的策略，使用DNA微芯片写了一本5.27兆比特的书，并通过使用下一代DNA测序来阅读这本书。
Digital information is accumulating at an astounding rate, straining our ability to store and archive it. DNA is among the most dense and stable information media known. The development of new technologies in both DNA synthesis and sequencing make DNA an increasingly feasible digital storage medium. We developed a strategy to encode arbitrary digital information in DNA, wrote a 5.27-megabit book using DNA microchips, and read the book by using next-generation DNA sequencing.