Laboratory-based X-ray phase-contrast imaging with misaligned optical elements
Laboratory-based X-ray phase-contrast imaging with misaligned optical elements
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DOI：
10.1063/1.4931778
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发表时间：
2015-09-21
影响因子：
4
通讯作者：
Olivo, Alessandro
中科院分区：
文献类型：
--
作者：
Endrizzi, Marco;Basta, Dario;Olivo, Alessandro
我们报告的实验室X射线相衬成像技术的基础上的边缘照明的原则，大大放宽了现有的限制，系统设置和数据采集，允许增加至少两个数量级的公差失调。该方法的鲁棒性进行了系统的研究，通过实验与我们的原型。为了评估图像质量对数据采集方案的依赖性，还进行了数值模拟。结果表明，在1度范围内的所有角度的掩模的定位误差，并在1毫米范围内的平移，不显着影响图像质量。我们还表明，如果不对准不超过几十微米，三个强度投影足以有效地检索样品的三个表示，允许优化的剂量或时间效率，即使是一个非理想的系统。(C)2015 AIP Publishing LLC.
We report on a laboratory X-ray phase-contrast imaging technique based on the edge illumination principle that substantially relaxes the existing limitations on system set up and data acquisition, allowing an increase in tolerance of misalignments by at least two orders of magnitude. The robustness of this approach was systematically studied by means of experiments with our prototype. Numerical simulations were also performed in order to assess the dependence of the image quality on the data acquisition scheme. The results show that errors in the positioning of the masks within a 1 degrees range for all the angles, and within 1 mm range of translation, do not noticeably affect image quality. We also show that, if the misalignment does not exceed few tens of micrometers, three intensity projections are sufficient to effectively retrieve the three representations of the sample, allowing for optimization of dose or time efficiency even with a non-ideal system. (C) 2015 AIP Publishing LLC.