c-myc amplification is associated with HER2 amplification and closely linked with cell proliferation in tissue microarray of nonselected breast cancers

c-myc amplification is associated with HER2 amplification and closely linked with cell proliferation in tissue microarray of nonselected breast cancers
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DOI:
10.1016/j.humpath.2005.04.016
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发表时间:
2005-06-01
期刊:
影响因子:
3.3
通讯作者:
Han, S
Han, S
中科院分区:
医学3区
文献类型:
--
作者:
Park, K;Kwak, K;Han, S

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采用组织微阵列技术荧光原位杂交分析了214例连续乳腺癌的c-myc和HER2扩增情况。扩增频率分别为15.4%(33/214)和23.3%(49/210)。c-myc扩增与HER2扩增显著相关(P
c-myc and HER2 amplification were analyzed on 214 consecutive breast cancers by fluorescence in situ hybridization using tissue microarray technology. The frequencies of amplification were 15.4% (33/214) and 23.3% (49/210), respectively. c-myc amplification was significantly associated with HER2 amplification (P