Automated lamellar therapeutic keratoplasty (ALTK) in the treatment of anterior to mid-stromal corneal pathologies
Automated lamellar therapeutic keratoplasty (ALTK) in the treatment of anterior to mid-stromal corneal pathologies
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DOI：
10.1111/j.1600-0420.2006.00722.x
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发表时间：
2006-12-01
期刊：
影响因子：
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通讯作者：
Sinha, Rajesh
中科院分区：
文献类型：
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作者：
Vajpayee, Rasik B.;Vasudendra, Nagaraj;Sinha, Rajesh
为评价全自动板层治疗性角膜移植(ALTK)治疗前中间质角膜病变的疗效，对15例15只眼使用ALTK系统(美国宾夕法尼亚州多伊尔斯敦的Moria/Microtek Inc.)进行了前瞻性临床研究。评价指标为裸眼和最佳矫正视力、角膜屈光度、角膜厚度、对比敏感度、眩光敏感度、术中手术时间和并发症、术后上皮化时间、植片清晰度和术后并发症。平均手术时间为46±9分钟。术后6个月BCVA、对比敏感度和眩光敏感度均有明显改善。术前平均小数点BCVA为0.08+/-0.03，术后6个月平均BCVA为0.33+/-0.30，其中11眼BCVA=6/18，平均上皮化时间为3天(1~10天)。
To evaluate the efficacy of automated lamellar therapeutic keratoplasty (ALTK) in the treatment of anterior to mid-stromal corneal pathologies.A prospective clinical study was undertaken in 15 eyes of 15 patients who underwent ALTK using the ALTK System((R)) (Moria/Microtek Inc., Doylestown, Pennsylvania, USA). The parameters evaluated were uncorrected and best corrected visual acuity (BCVA), keratometry, pachymetry, contrast sensitivity, glare acuity, intraoperative surgical time and complications, postoperative time to epithelialization, graft clarity and postoperative complications.The mean surgical time was 46 +/- 9 mins. The BCVA, contrast sensitivity and glare acuity significantly improved at 6 months postoperatively. The mean decimal BCVA was 0.08 +/- 0.03 preoperatively, which improved to 0.33 +/- 0.30 at 6 months, when 11 eyes had BCVA >= 6/18. The median epithelialization time was 3 days (range 1-10 days).Automated lamellar therapeutic keratoplasty appears to be safe and effective for diseases affecting the anterior to mid-stroma of the cornea.