Genetic analysis of eight population groups living in Taiwan using a 13 X-chromosomal STR loci multiplex system
Genetic analysis of eight population groups living in Taiwan using a 13 X-chromosomal STR loci multiplex system
复制标题
使用 13 X 染色体 STR 位点多重系统对台湾八个人群进行遗传分析
DOI：
10.1007/s00414-009-0414-z
复制
发表时间：
2009
影响因子：
2.1
通讯作者：
T. Ko
中科院分区：
文献类型：
--
作者：
H. Hwa;James Chun;Yih;H. Yin;Ya;L. Tseng;Yidi Su;T. Ko
13个X染色体短串联重复序列（STR）多重系统（DXS 6807，DXS 8378，DSX 9902，DXS 7132，DXS 9898，DXS 6809，DXS 6789，DXS 7424，DXS 101，GATA 172 D 05，HPRTB，DXS 8377和DXS 7423）在1,037个DNA样本中进行了测试，这些样本来自目前居住在台湾的8个人群。等位基因频率在不同人群中的分布不同。DXS 8377和DXS 101是这8个群体中多态性最高的两个位点，而DXS 7423是大多数群体中信息量最少的标记。群体间的遗传距离和构建的系统发育树显示亚洲人和高加索人群体之间的遗传距离较长，以及隔离的陶人口。系统发育树将种群分为与其民族地理关系相适应的聚类。这13个X染色体短串联重复序列多重系统提供了相当数量的多态性模式在不同的人群。该系统可用于法医鉴定个案工作和民族地理学研究。
A 13 X-chromosomal short tandem repeat (STR) multiplex system (DXS6807, DXS8378, DSX9902, DXS7132, DXS9898, DXS6809, DXS6789, DXS7424, DXS101, GATA172D05, HPRTB, DXS8377, and DXS7423) was tested on 1,037 DNA samples from eight population groups currently living in Taiwan. Different distributions of the allelic frequencies in different populations were presented. DXS8377 and DXS101 were the two most polymorphic loci in these eight populations, whereas DXS7423 was the least informative marker in most of the populations studied. The genetic distances between the populations and the constructed phylogenetic tree revealed a long genetic distance between Asian and Caucasian populations as well as isolation of the Tao population. The phylogenetic tree grouped populations into clusters compatible with their ethnogeographic relationships. This 13 X-chromosomal short tandem repeat multiplex system offers a considerable number of polymorphic patterns in different populations. This system can be useful in forensic identification casework and ethnogeographic research.