The anatomic location of pancreatic cancer is a prognostic factor for survival
The anatomic location of pancreatic cancer is a prognostic factor for survival
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DOI：
10.1080/13651820802291233
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发表时间：
2008-10-01
期刊：
影响因子：
2.9
通讯作者：
Kim, Joseph
中科院分区：
文献类型：
--
作者：
Artinyan, Avo;Soriano, Perry A.;Kim, Joseph
背景与头部（HD）病变相比，体部和尾部（BT）的胰腺癌似乎具有较差的生存率。我们推测，潜在的差异，结果可能与肿瘤的位置。我们的目的是研究肿瘤位置和生存率之间的关系。方法.监测、流行病学和最终结果登记研究确定了1988年至2004年间33,752例胰腺癌患者和6443例接受癌症导向手术的患者。评估了生存率的差异以及肿瘤位置和临床因素之间的关系。进行多因素分析以确定肿瘤位置的预后意义。结果整个队列的中位生存期为5个月，BT组显著低于HD组（4个月vs. 6个月，p
Background. Pancreatic cancers of the body and tail (BT) appear to have poorer survival compared with head (HD) lesions. We hypothesized that potential disparities in outcome may be related to tumor location. Our objective was to examine the relationship between tumor location and survival. Methods. The Surveillance, Epidemiology, and End Results registry identified 33,752 patients with pancreatic adenocarcinoma and 6443 patients who underwent cancer-directed surgery between 1988 and 2004. Differences in survival and relationships between tumor location and clinical factors were assessed. Multivariate analysis was performed to determine the prognostic significance of tumor location. Results. Median survival for the entire cohort was five months and was significantly lower for BT compared to HD lesions (four vs. six months, p