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DOI：
10.1038/kisup.2012.9
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发表时间：
2012-05-15
影响因子：
5.5
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中科院分区：
文献类型：
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2011肾脏疾病：改善肾小球肾炎（GN）的全球结果（KDIGO）临床实践指南旨在帮助医生照顾成人和儿童肾小球肾炎。指南的制定遵循了一个明确的证据审查和评估过程。该指南包含关于各种肾小球疾病的章节：儿童类固醇敏感肾病综合征；儿童类固醇抵抗性肾病综合征；的最小改变疾病;特发性局灶节段性肾小球硬化；特发性膜性肾病；membranoproliferative肾小球肾炎;感染相关性肾小球肾炎;IgA肾病;Henoch-Schönlein紫癜性肾炎；狼疮肾炎;保西免疫局灶性和节段性坏死性肾小球肾炎；抗肾小球基底膜抗体肾小球肾炎。治疗方法在每章中都有介绍，指南建议是基于对相关试验的系统评价。对证据质量和建议强度的评估采用GRADE方法。讨论了证据的局限性，并对今后的研究提出了具体建议。
The 2011 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for Glomerulonephritis (GN) aims to assist practitioners caring for adults and children with GN. Guideline development followed an explicit process of evidence review and appraisal. The guideline contains chapters on various glomerular diseases: steroid-sensitive nephrotic syndrome in children; steroid-resistant nephrotic syndrome in children; minimal-change disease; idiopathic focal segmental glomerulosclerosis; idiopathic membranous nephropathy; membranoproliferative glomerulonephritis; infection-related glomerulonephritis; IgA nephropathy; Henoch-Schönlein purpura nephritis; lupus nephritis; pauci-immune focal and segmental necrotizing glomerulonephritis; and anti-lomerular basement membrane antibody glomerulonephritis. Treatment approaches are addressed in each chapter and guideline recommendations are based on systematic reviews of relevant trials. Appraisal of the quality of the evidence and the strength of recommendations followed the GRADE approach. Limitations of the evidence are discussed and specific suggestions are provided for future research.