Circadian rhythm of blood glucose values in critically ill patients
Circadian rhythm of blood glucose values in critically ill patients
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DOI：
10.1097/01.ccm.0000253814.78836.43
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发表时间：
2007-02-01
影响因子：
8.8
通讯作者：
Stow, Peter
中科院分区：
文献类型：
--
作者：
Egi, Moritoki;Bellomo, Rinaldo;Stow, Peter
目的：测试危重患者血糖控制是否存在昼夜节律，以及早晨血糖是否可以准确替代总体血糖控制。设计：回顾性多中心观察研究。设置。三家三级医院和一家附属私立医院的重症监护病房。患者：由 8,307 名连续重症患者组成的队列。干预措施。从电子存储的测量值中提取血糖值。从单位和医院数据库中提取人口统计和结果数据。每个 24 小时周期内血糖控制变化的统计评估。测量和主要结果。我们研究了 8,307 名患者的 208,362 次血糖测量（5.5 次测量/天/人）。每家医院都有血糖控制的昼夜节律（p
Objective: To test whether there is a circadian rhythm of blood glucose control in critically ill patients and whether morning blood glucose is an accurate surrogate of overall blood glucose control.Design: Retrospective multiple-center observational study.Setting. Intensive care units of three tertiary hospitals and one affiliated private hospital.Patients: Cohort of 8,307 consecutive critically ill patients.Interventions.Extraction of blood glucose values from electronically stored measurements. Extraction of demographic and outcome data from unit and hospital databases. Statistical assessment of variations in blood glucose control over each 24-hr cycle.Measurements and Main Results. We studied 208,362 blood glucose measurements in 8,307 patients (5.5 measurements/day/ person). In each hospital, there was a circadian rhythm of blood glucose control (p