Burden of chronic sleep maintenance insomnia characterized by nighttime awakenings among anxiety and depression sufferers: results of a national survey.
Burden of chronic sleep maintenance insomnia characterized by nighttime awakenings among anxiety and depression sufferers: results of a national survey.
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DOI：
10.4088/pcc.09m00824gry
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发表时间：
2010-01-01
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影响因子：
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通讯作者：
Drake, Christopher L
中科院分区：
文献类型：
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作者：
Bolge, Susan C;Joish, Vijay N;Drake, Christopher L
目的：确定并量化抑郁症和焦虑症患者以夜间觉醒 (CINA) 为特征的慢性睡眠维持性失眠的负担。方法：数据来自 2006 年美国国家健康与健康调查，这是一项针对美国成年人的年度横断面研究。分析仅限于诊断为抑郁或焦虑的受访者。 CINA一词被定义为经历夜间醒来，入睡无困难，每周至少两次，持续1个月以上，对日常生活产生中度至重度影响。结果包括过去 6 个月的资源利用情况、工作生产力和活动损害调查问卷以及医疗结果研究 8 项简短健康调查 (SF-8)。使用线性回归模型评估 CINA 对人口统计学和合并症调整结果的独立影响。结果：在抑郁症患者中，643 名经历过 CINA，1,675 名没有失眠。在焦虑症患者中，476 人经历过 CINA，1,356 人没有经历过失眠。调整人口统计数据和合并症后，患有 CINA 的抑郁症患者的就诊次数增加了 2.4 次，工作障碍增加了 13.2%（全职雇员），活动障碍增加了 18.2%，SF-8 身体和心理总分比非失眠患者低 4.8 和 6.7 分（所有 P < .001）。患有 CINA 的焦虑症患者就诊次数增加了 3.0 次，工作障碍增加了 15.8%（在全职雇员中），活动障碍增加了 20.4%，SF-8 身体和心理总分比非失眠患者低 5.4 和 7.6 分（所有 P < .001）。结论：在抑郁症和焦虑症患者中，相对孤立的 CINA 与医疗保健利用率和医疗保健利用率的显着负面影响相关。其相关成本、与健康相关的生活质量和工作生产力。
OBJECTIVE: To identify and quantify the burden of chronic sleep maintenance insomnia characterized by nighttime awakenings (CINA) among depression and anxiety sufferers.METHOD: Data were obtained from the 2006 US National Health and Wellness Survey, an annual cross-sectional study of US adults. Analyses were limited to respondents diagnosed with depression or anxiety. The term CINA was defined as experiencing nighttime awakenings, without difficulty falling asleep, at least twice per week for more than 1 month that have moderate-severe impact on daily life. Outcomes included resource utilization in past 6 months, the Work Productivity and Activity Impairment questionnaire, and the Medical Outcomes Study 8-item Short-Form Health Survey (SF-8). Independent effects of CINA on outcomes adjusting for demographics and comorbidity were assessed using linear regression models.RESULTS: Among depression sufferers, 643 experienced CINA and 1,675 experienced no insomnia. Among anxiety sufferers, 476 experienced CINA and 1,356 experienced no insomnia. Adjusting for demographics and comorbidity, depression sufferers with CINA had 2.4 more provider visits, 13.2% greater work impairment (among full-time employed), 18.2% greater activity impairment, and SF-8 physical and mental summary scores that were 4.8 and 6.7 points lower than noninsomnia sufferers (P < .001 for all). Anxiety sufferers with CINA had 3.0 more provider visits, 15.8% greater work impairment (among full-time employed), 20.4% greater activity impairment, and SF-8 physical and mental summary scores that were 5.4 and 7.6 points lower than noninsomnia sufferers (P < .001 for all).CONCLUSIONS: Among depression and anxiety sufferers, CINA in relative isolation was associated with a significant negative impact on health care utilization and its associated costs, health-related quality of life, and work productivity.