Effect of 1-alpha-hydroxycholecalciferol on magnesium metabolism in chronic renal failure.
Effect of 1-alpha-hydroxycholecalciferol on magnesium metabolism in chronic renal failure.
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1-α-羟基胆钙化醇对慢性肾功能衰竭镁代谢的影响。
DOI：
10.1136/bmj.1.6055.211
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发表时间：
1977
影响因子：
--
通讯作者：
M. Bartlett
中科院分区：
文献类型：
--
作者：
J. Kanis;R. Smith;R. Walton;M. Bartlett
我们研究了2例慢性肾功能衰竭和肾性骨病患者（病例1和2;血浆肌酐分别为480，umol/l（5 4 mg/100 ml）和640，umol/l（7-2 mg/100 ml））在口服1-m-OHD 3 2 teg/天治疗前和治疗期间的钙和镁2外部平衡（见图）。病例1在治疗的前4天内钙潴留显著增加，病例2（一名肾性侏儒，钙摄入量很少）在治疗18个月后钙潴留显著增加，但镁平衡未发生显著变化。
We studied the external balances of calcium and magnesium2 in two patients with chronic renal failure and renal bone disease (cases 1 and 2; plasma creatinine 480 ,umol/l (5 4 mg/100 ml) and 640 ,umol/l (7-2 mg/100 ml) respectively) before and during treatment with 1-m-OHD3 2 teg/daily by mouth (see figure). Considerable increases in calcium retention during the first four days of treatment in case 1, and after 18 months in case 2 (a renal dwarf who ate little calcium), were unaccompanied by significant changes in magnesium balance.