Plasma concentrations of sodium valproate: Their clinical value
Plasma concentrations of sodium valproate: Their clinical value
复制标题
丙戊酸钠的血浆浓度：其临床价值
DOI：
10.1002/ana.410140107
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发表时间：
1983
影响因子：
11.2
通讯作者：
D. Chadwick
中科院分区：
文献类型：
--
作者：
D. Turnbull;M. Rawlins;D. Weightman;D. Chadwick
Plasma valproate concentrations were monitored prospectively in 54 previously untreated adult patients with epilepsy. Dose and plasma concentration were highly correlated. Adverse effects were common in association with plasma levels above 100 μg/ml. In patients suffering tonic‐clonic seizures without focal symptoms, no seizures occurred when plasma levels were higher than 50 μg/ml. In patients with partial seizures, it was difficult to define a lower limit to a therapeutic range.
