Adverse working events in patients with multiple sclerosis
Adverse working events in patients with multiple sclerosis
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DOI：
10.1007/s10072-016-2737-0
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发表时间：
2017-02-01
影响因子：
3.3
通讯作者：
Nocentini, Ugo
中科院分区：
文献类型：
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作者：
Incerti, Chiara Concetta;Argento, Ornella;Nocentini, Ugo
多发性硬化症（MS）和工作状态最近引起了人们的极大兴趣。疲劳、身体残疾、认知和心理障碍与失业以及日常活动中的事故有关。我们研究的目的是确定工作场所不同类型事故 (AWE) 的频率以及就业 (MSe) 和失业 (MSu) 多发性硬化症患者之间可能的临床差异。招募了 60 名多发性硬化症患者（31 名就业者，29 名失业者）和 20 名健康对照受试者。所有受雇的参与者都被要求填写一份临时调查问卷，以收集过去 2 个月在工作场所发生的 AWE 和相关风险。还评估了身体、认知、情绪和疲劳评估。疾病和颠簸以及颠簸和险些跌倒的风险导致了 MSe 中最常见的 AWE 和风险。有趣的是，这些 AWE 主要在患有焦虑、抑郁和认知疲劳的受试者中观察到，而不是取决于身体损伤的严重程度。此外，焦虑和愤怒等心理因素似乎在决定 AWE 方面发挥着至关重要的作用。这项研究提供了 AWE 发生的数据，并提出了多发性硬化症工作场所负面事件的可能机制。这对于规划多发性硬化症患者的 AWE 预防策略可能很重要。
Multiple sclerosis (MS) and working status have recently arisen great interest. Fatigue, physical disability, cognition, and psychological disturbances have been linked to unemployment, as well to accidents during daily activities. The aim of our study was to determine frequency of different types of accidents at workplace (AWE) and possible clinical differences among employed (MSe) and unemployed (MSu) MS patients. Sixty MS patients (31 employed, 29 unemployed) and twenty healthy control subjects were recruited. All employed participants were requested to complete an ad-hoc questionnaire to collect AWE and related risks occurring at workplace in the past 2 months. Physical, cognitive, mood, and fatigue evaluations were also assessed. Illness and bumps along with risk of bumps and near falls resulted the most frequent AWE and risks occurring in MSe. Interestingly, those AWE were mostly observed among subjects with anxiety, depression, and cognitive fatigue rather than depending on severity of physical impairment. Moreover, psychological aspects, like anxiety and anger, seemed to play a crucial role in determining AWE. This study provides data on AWE occurrence and suggests possible mechanisms underlying negative events at workplace in MS. This might be important for planning strategies of AWE prevention in MS patients.