Sex differences and similarities in the management and outcome of stroke patients
Sex differences and similarities in the management and outcome of stroke patients
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DOI：
10.1161/01.str.31.8.1833
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发表时间：
2000-08-01
期刊：
影响因子：
8.3
通讯作者：
Tu, JV
中科院分区：
文献类型：
--
作者：
Holroyd-Leduc, JM;Kapral, MK;Tu, JV
背景和目的：先前的研究已经证实了心血管疾病患者的治疗和预后的性别差异。然而，关于中风患者是否存在类似的性别差异的数据很少。我们进行了一项研究，以确定安大略省医院收治的急性中风患者是否存在性别差异。方法：使用相关的管理数据库，我们进行了一项基于人群的队列研究。这些数据库载有1993年4月至1996年3月期间从安大略省急症医院出院的44832名经最负责任诊断为急性中风的病人的资料。测量的主要结果包括合并症的性别差异、康复服务的使用、抗血小板治疗和抗凝血药物的使用（仅限年龄大于或等于65岁的老年中风幸存者）、出院目的地和死亡率。结果：男性卒中患者比女性卒中患者有缺血性心脏病史的可能性更高（分别为18.1%和15.3%）
Background and Purpose-Previous studies have documented sex differences in the management and outcome of patients with cardiovascular disease. However, little data exist on whether similar sex differences exist in stroke patients. We conducted a study to determine whether sex differences exist in patients with acute stroke admitted to Ontario hospitals.Methods-Using linked administrative databases, we performed a population-based cohort study. The databases contained information on all 44 832 patients discharged from acute-care hospitals in Ontario between April 1993 and March 1996 with a most responsible diagnosis of acute stroke. The main outcomes measured consisted of sex differences in comorbidities, the use of rehabilitative services, the use of antiplatelet therapy and anticoagulants tin elderly stroke survivors aged greater than or equal to 65 years only), discharge destination, and mortality.Results-Male stroke patients were more likely than female stroke patients to have a history of ischemic heart disease (18.1% versus 15.3%, respectively; P