Race moderates the relationship between obesity and colorectal cancer screening in women.

Race moderates the relationship between obesity and colorectal cancer screening in women.
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DOI:
10.1007/s10552-009-9469-x
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发表时间:
2010-03
影响因子:
2.3
通讯作者:
Pignone, Michael P.
Pignone, Michael P.
中科院分区:
医学4区
文献类型:
--
作者:
Leone, Lucia A.;Campbell, Marci K.;Satia, Jessie A.;Bowling, J. Michael;Pignone, Michael P.

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确定当按种族分层时,肥胖与女性结直肠癌(CRC)筛查使用之间的关系是否存在差异。利用2005年全国健康访谈调查的全国代表性数据,我们研究了50岁及以上白色和非洲裔美国妇女肥胖与CRC筛查之间的关系。筛查使用变量表明,如果一个女人是最新的任何CRC筛查试验,结肠镜检查,或FOBT。我们使用多变量逻辑回归模型,包括交互作用,以确定是否种族缓和肥胖筛查的关系。我们还使用直接标准化模型协变量计算了调整后的最新结肠镜检查率。对于任何CRC筛查试验(相互作用P = 0.04)和结肠镜检查(相互作用P = 0.01),肥胖和筛查之间的关系因种族而异,但FOBT没有。肥胖白色女性的结肠镜检查率(30.2%,95% CI 25.9-34.8)低于非肥胖白色女性(39.1%,95% CI 36.1-42.2)。另一方面,肥胖的非裔美国女性的结肠镜检查率(41.2%,95%CI 31.6-51.4)高于非肥胖女性(35.6%,95%CI 28.3-43.6)。总的来说,肥胖白色女性的结肠镜检查率最低。肥胖与白色女性较低的CRC筛查率相关,但与非洲裔美国女性无关。
To determine if the relationship between obesity and usage of colorectal cancer (CRC) screening in women varies when stratifying by race. Using nationally representative data from the 2005 National Health Interview Survey, we examined the relationship between obesity and CRC screening for white and African-American women aged 50 and older. Screening usage variables indicated if a woman was up-to-date for any CRC screening test, colonoscopy, or FOBT. We used multivariable logistic regression models that included interaction terms to determine if race moderates the obesity-screening relationship. We also calculated adjusted up-to-date colonoscopy rates using direct standardization to model covariates. The relationship between obesity and screening differed by race for any CRC screening test (P = 0.04 for interaction) and for colonoscopy (P = 0.01 for interaction), but not for FOBT. Obese white women had a lower adjusted colonoscopy rate (30.2%, 95% CI 25.9–34.8) than non-obese white women (39.1%, 95% CI 36.1–42.2). Obese African-American women, on the other hand, had a higher adjusted colonoscopy rate (41.2%, 95% CI 31.6–51.4) than their non-obese counterparts (35.6%, 95% CI 28.3–43.6). Overall, adjusted colonoscopy rates were lowest among obese white women. Obesity is associated with lower CRC screening rates in white, but not African-American women.
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