The blood-ocular barriers under osmotic stress. Studies on the freeze-dried eye.
The blood-ocular barriers under osmotic stress. Studies on the freeze-dried eye.
复制标题
渗透压下的血眼屏障。
DOI：
10.1001/archopht.1976.03910040006002
复制
发表时间：
1976
影响因子：
--
通讯作者：
S. Rapoport
中科院分区：
文献类型：
--
作者：
A. Laties;S. Rapoport
灵长类动物的血眼屏障严重渗透应激反应的区域差异进行了测量。通过荧光显微镜将标记染料定位在已经冻干以防止扩散的组织中。在严重的渗透压下，睫状突的形式和功能严重受损，而虹膜则幸免于难。视网膜色素上皮屏障的破坏是普遍的，而大面积的视网膜血管保留正常的渗透性特征。色素上皮屏障机制在视盘周围区域比在赤道区更容易受到渗透应力的影响。
Regional differences in the response of primate blood-ocular barriers to severe osmotic stress were measured. Marker dyes were localized by fluorescence microscopy in tissues that had been freeze-dried to prevent diffusion. Under severe osmotic stress, the form and the function of the ciliary process are grossly compromised while the iris is spared. Breakdown of the retinal pigment epithelial barrier is widespread, while the retinal blood vessels in large areas retain normal permeability characteristics. The pigment epithelial barrier mechanism is substantially more susceptible to osmotic stress in the region surrounding the optic disc than in the equatorial area.