The relevance of intestinal dysbiosis in liver transplant candidates
The relevance of intestinal dysbiosis in liver transplant candidates
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DOI：
10.1111/tid.12352
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发表时间：
2015-04-01
影响因子：
2.6
通讯作者：
Krawczyk, M.
中科院分区：
文献类型：
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作者：
Grat, M.;Holowko, W.;Krawczyk, M.
BackgroundThe gut microbial ecosystem plays an important role in the pathogenesis of liver diseases. However, the association of microbial community structure with the severity of liver dysfunction is not completely understood.MethodsFecal microflora was assessed in 40 patients with liver cirrhosis listed for primary liver transplantation (LT). Independent associations between fecal microbial counts and serum bilirubin, serum creatinine, international normalized ratio (INR), and the Model for End-stage Liver Disease (MELD) score were established in multiple linear regression models.ResultsBifidobacterium (standardized regression coefficient [s]=-0.549; P
