Alterations of cortical and trabecular architecture are associated with fractures in postmenopausal women, partially independent of decreased BMD measured by DXA: The OFELY study

Alterations of cortical and trabecular architecture are associated with fractures in postmenopausal women, partially independent of decreased BMD measured by DXA: The OFELY study
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DOI:
10.1359/jbmr.061206
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发表时间:
2007-03-01
影响因子:
6.2
通讯作者:
Delmas, Pierre D.
Delmas, Pierre D.
中科院分区:
医学1区
文献类型:
--
作者:
Sornay-Rendu, Elisabeth;Boutroy, Stephanie;Delmas, Pierre D.

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在一项绝经后女性骨折的病例对照研究中,我们通过HR-pQCT系统评估了aBMD降低和结构受损的作用。椎体和非椎体骨折与骨小梁和皮质骨的低体积骨密度和结构改变相关,与DXA评估的骨密度无关。
We assessed the role of low aBMD and impaired architecture-assessed by an HR-pQCT system-in a case-control study of postmenopausal women with fractures. Vertebral and nonvertebral fractures are associated with low volumetric BMD and architectural alterations of trabecular and cortical bone, independent of aBMD assessed by DXA.