Synthesis and aminolysis of polysaccharide carbonates
Synthesis and aminolysis of polysaccharide carbonates
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DOI：
10.1007/s10570-012-9819-9
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发表时间：
2013-02-01
期刊：
影响因子：
5.7
通讯作者：
Heinze, Thomas
中科院分区：
文献类型：
--
作者：
Elschner, Thomas;Ganske, Kristin;Heinze, Thomas
以对硝基氯甲酸苯酯、氯甲酸苯酯和氟甲酸苯酯为原料，合成了可溶性好的右旋糖酐、纤维素、淀粉和支链淀粉芳基碳酸酯。使用脂族胺或苄基胺对所得产物进行氨解，得到新的可溶性多糖氨基甲酸酯。研究了多糖、试剂、反应温度等因素对反应效率的影响。因此，开发了一种合成策略，用于简单有效地设计多糖基材料的结构。通过核磁共振、紫外-可见和红外光谱、元素分析和尺寸排阻色谱对产物进行了表征。
Well soluble dextran-, cellulose-, starch-, and pullulan aryl carbonates were synthesized applying p-NO2-phenyl chloroformate, phenyl chloroformate, and phenyl fluoroformate. Aminolysis of the products obtained, using aliphatic amines or benzyl amines, yield novel soluble polysaccharide carbamates. The influence of the reaction conditions on the reaction efficiency depending on polysaccharide, reagent, and reaction parameters including temperature was studied. Thus a synthesis strategy was developed for the easy and efficient design of structures of polysaccharide-based materials. The products were characterized by means of NMR-, UV-Vis- and FTIR spectroscopy, elemental analysis, and size exclusion chromatography.