Multi-photon microscopy based on resonant four-wave mixing of colloidal quantum dots

Multi-photon microscopy based on resonant four-wave mixing of colloidal quantum dots
复制标题

基于胶体量子点共振四波混合的多光子显微镜

DOI:
10.1117/12.807968
复制
发表时间:
2009
期刊:
--
影响因子:
--
通讯作者:
Masia F
Masia F
中科院分区:
--
文献类型:
--
作者:
Masia F

文献摘要

参考文献

相似文献

我们展示了一种新的多光子成像模式的基础上检测四波混频(FWM)从胶体纳米粒子。四波混频是一种三阶信号,它可以与CdSe/ZnS量子点的基态激子跃迁共振激发和检测。相干四波混频信号检测干涉拒绝不相干的背景,提高图像对比度相比,荧光方法。我们测量的横向和轴向分辨率分别为140 nm和590 nm,大大超过了单光子衍射极限。我们还展示了量子点标记的高尔基体结构的HepG 2细胞的光学成像。
We demonstrate a novel multi-photon imaging modality based on the detection of four-wave mixing (FWM) from colloidal nanoparticles. Four-wave mixing is a third-order signal which can be excited and detected in resonance with the ground-state excitonic transition of CdSe/ZnS quantum dots. The coherent FWM signal is detected interferometrically to reject incoherent backgrounds for improved image contrast compared to fluorescence methods. We measure transversal and axial resolutions of 140nm and 590nm respectively, significantly beating the one-photon diffraction limit. We also demonstrate optical imaging of quantum-dot-labeled Golgi structures of HepG2 cells.
DOI: --
发表时间: 2006
期刊:
影响因子: --
作者:
Michiel Müller
通讯作者: Michiel Müller
DOI: 10.1088/0953-8984/19/29/295201
发表时间: 2007-06
期刊: Journal of Physics: Condensed Matter
影响因子: --
作者:
P. Borri;W. Langbein
通讯作者: P. Borri;W. Langbein
DOI: 10.1126/science.2321027
发表时间: 1990-04-06
期刊: SCIENCE
影响因子: 56.9
作者:
DENK, W;STRICKLER, JH;WEBB, WW
通讯作者: WEBB, WW