Reconstructing the Deep Population History of Central and South America
Reconstructing the Deep Population History of Central and South America
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DOI：
10.1016/j.cell.2018.10.027
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发表时间：
2018-11-15
期刊：
影响因子：
64.5
通讯作者：
Reich, David
中科院分区：
文献类型：
--
作者：
Posth, Cosimo;Nakatsuka, Nathan;Reich, David
我们报告了来自49个个体的全基因组古代DNA，它们形成了四个平行的时间横断面，分别位于伯利兹、巴西、中央安第斯山脉和南锥体，每个横断面至少可以追溯到9000年前。共同的祖先人口只从两个早期分支中的一个迅速辐射出来，这些分支促成了今天的美洲原住民。我们记录了北美和南美之间两个以前从未被赏识的基因流动。一种影响中安第斯山脉的时间类似于4200年前，而另一种解释了与克洛维斯文化相关的最古老的北美基因组与来自智利、巴西和伯利兹的最古老的中美洲和南美洲之间的亲缘关系。然而，这并不是后来南美洲人的主要来源，因为其他古代个体来自与克洛维斯相关基因组没有特定亲缘关系的血统，这表明至少在9000年前开始了种群更替，随后在多个地区的种群基本上保持了连续性。
We report genome-wide ancient DNA from 49 individuals forming four parallel time transects in Belize, Brazil, the Central Andes, and the Southern Cone, each dating to at least similar to 9,000 years ago. The common ancestral population radiated rapidly from just one of the two early branches that contributed to Native Americans today. We document two previously unappreciated streams of gene flow between North and South America. One affected the Central Andes by similar to 4,200 years ago, while the other explains an affinity between the oldest North American genome associated with the Clovis culture and the oldest Central and South Americans from Chile, Brazil, and Belize. However, this was not the primary source for later South Americans, as the other ancient individuals derive from lineages without specific affinity to the Clovis-associated genome, suggesting a population replacement that began at least 9,000 ago and was followed by substantial population continuity in multiple regions.