Cervical cancer prevention: safety, acceptability, and feasibility of a single-visit approach in Accra, Ghana
Cervical cancer prevention: safety, acceptability, and feasibility of a single-visit approach in Accra, Ghana
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DOI：
10.1016/j.ajog.2006.12.031
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发表时间：
2007-04-01
影响因子：
9.8
通讯作者：
Adadevoh, Sydney
中科院分区：
文献类型：
--
作者：
Blumenthal, Paul D.;Gaffikin, Lynne;Adadevoh, Sydney
目的：本研究的目的是评估单次就诊宫颈癌预防方法的安全性和可接受性，该方法结合目视检查宫颈、醋酸冲洗 (VIA) 和冷冻疗法。 研究设计：该研究是观察性的。九名临床医生接受了 VIA 和冷冻疗法的培训。 18 个月内，3665 名女性接受了 VIA 测试。如果呈阳性且符合条件，则立即进行冷冻治疗。对接受治疗的女性进行了3个月和1年的随访。结果：检测阳性率为13.2%。在符合条件的人中，70.2% 和 21% 分别接受了立即或延迟治疗。没有记录到重大并发症，5.6% 的患者在冷冻治疗后出现了明显的问题。在接受治疗的人中，超过 90% 的人对他们的经历表示满意，96% 的人有可识别的鳞柱交界处。治疗 1 年后，只有 2.6% (6/232) 的检测结果呈阳性。结论：事实证明，使用 VIA 和冷冻疗法的单次就诊方法在非洲城市环境中是安全、可接受且可行的。
OBJECTIVE: The purpose of this study was to assess the safety and acceptability of a single-visit approach to cervical cancer prevention combining visual inspection of the cervix with acetic acid wash (VIA) and cryotherapy.STUDY DESIGN: The study was observational. Nine clinicians were trained in VIA and cryotherapy. Over 18 months 3665 women were VIA-tested. If positive and eligible, cryotherapy was offered immediately. Treated women were followed-up at 3 months and 1 year.RESULTS: The test-positive rate was 13.2%. Of those eligible, 70.2% and 21% received immediate or delayed treatment, respectively. No major complications were recorded, and 5.6% presented for a perceived problem post-cryotherapy. Among those treated over 90% expressed satisfaction with their experience, and 96% had an indentifiable squamo-columnar junction. Only 2.6% (6/232) were test positive, 1-year posttreatment.CONCLUSION: A single-visit approach using VIA and cryotherapy proved to be safe, acceptable, and feasible in an urban African setting.