Preparation of J-aggregate liposome dispersions and their chromic transformation.
Preparation of J-aggregate liposome dispersions and their chromic transformation.
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DOI：
10.1021/la049569u
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发表时间：
2004-06
期刊：
影响因子：
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通讯作者：
N. Kato;J. Prime;Kiyofumi Katagiri;F. Caruso
中科院分区：
文献类型：
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作者：
N. Kato;J. Prime;Kiyofumi Katagiri;F. Caruso
我们报道了由两亲性merocyanine染料（MD）形成的j聚集体的水脂质体分散体的制备。一系列形成脂质体的脂质以不同的MD与脂质摩尔比与MD j聚集体一起分散。以1,2-二肉豆醇- n-甘油-3-磷酸胆碱（DMPC）为原料，在MD与DMPC的比例为0.16时制备的MD j -聚集体具有良好的分散性；也就是说，即使在沉淀后，它们也可以很容易地再分散而不发生絮凝。通过对MD分子使用不同的反离子，得到了两种类型的j -聚集体分散体，一种在635 nm处表现出吸收带（j波段）（型I），另一种在600 nm处表现出吸收带（型II）。作为使用MD j聚集体脂质体分散体的一个例子，证明了MD j聚集体的热致变色转化。当分散体受热后，在一定温度（T(disp)）下，I型j -团聚体转变为II型j -团聚体。确定了控制变换速度和T（disp）值的参数。
We report the preparation of aqueous liposome dispersions of J-aggregates formed by the amphiphilic merocyanine dye (MD). A series of liposome-forming lipids were dispersed together with MD J-aggregates at different molar ratios of MD to lipid. The MD J-aggregate dispersions prepared with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) at the MD to DMPC ratio of 0.16 exhibit good dispersibility; that is, they can be readily redispersed without any flocculation even after their precipitation. By use of different counterions for the MD molecules, two types of J-aggregate dispersions, one that exhibits an absorption band (J-band) at 635 nm (type I) and the other at 600 nm (type II), were obtained. As an example of the use of MD J-aggregates liposome dispersions, the thermochromic transformation of MD J-aggregates was demonstrated. When the dispersions are heated, J-aggregates of type I transformed into type II at a certain temperature (T(disp)). The parameters that control the speed of the transformation and the value of T(disp) were determined.