References for growth and pubertal development from birth to 21 years in Flanders, Belgium

References for growth and pubertal development from birth to 21 years in Flanders, Belgium
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DOI:
10.3109/03014460903049074
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发表时间:
2009-01-01
影响因子:
1.7
通讯作者:
Hoppenbrouwers, K.
Hoppenbrouwers, K.
中科院分区:
医学4区
文献类型:
--
作者:
Roelants, M.;Hauspie, R.;Hoppenbrouwers, K.

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背景:由于长度和身高的长期趋势,生长参考需要定期更新。比利时最近使用的参考图表是基于 30 多年前收集的样本,之前尚未建立体重指数 (BMI) 和青春期发育的参考。目标:根据比利时佛兰德斯儿童的代表性样本,建立从出生到 21 岁的身高、体重、BMI、头围和青春期发育的当代横截面参考图表。主题和方法:15 2002 年至 2004 年对 989 名 0-25 岁的比利时裔健康受试者进行了测量。使用 LMS 方法拟合生长曲线,并使用广义相加模型对 8690 名 6-22 岁受试者的现状数据估计青春期发育的百分位。结果:在 5 岁以上儿童中观察到身高和体重呈正向长期趋势。男孩的成人平均身高每十年增加 1.2 厘米,女孩每十年增加 0.8 厘米;男孩体重中位数每十年增加 0.9 公斤,女孩每十年增加 1.0 公斤,而且体重分布变得更加不平衡。除较高的百分位数外,BMI 曲线与其他人群的曲线相当。这反映出超重和肥胖的患病率日益增加。过去 50 年来,初潮的中位年龄(13.0 岁)没有再提前。女孩初潮和 B2 的中位年龄以及男孩 G2 或 T4 的中位年龄与其他西欧估计值相当,但大约 10% 在 9 岁之前进入 G2/T4。结论:身高和体重持续的长期趋势使得比利时以前使用的生长图表变得过时。引入了新的生长和青春期发育代表性图表。对于体重监测,建议使用现有的 BMI 生长图表。
Background: Due to the secular trend in length and height, growth references need to be updated regularly. Reference charts that were until recently used in Belgium are based on samples collected more than 30 years ago, and references for body mass index (BMI) and pubertal development have not been established before.Aims: To establish contemporary cross-sectional reference charts for height, weight, BMI, head circumference, and pubertal development from birth to 21 years of age, based on a representative sample of children from Flanders, Belgium.Subjects and methods: 15 989 healthy subjects of Belgian origin, 0-25 years of age, were measured in 2002-2004. Growth curves were fitted with the LMS method, and percentiles for the pubertal development were estimated with generalized additive models on status quo data from 8690 subjects aged 6-22 years of age.Results: A positive secular trend in height and weight is observed in children above 5 years of age. Adult median height has increased by 1.2 cm/decade in boys and 0.8 cm/decade in girls; median weight by 0.9 kg/decade in boys, and 1.0 kg/decade in girls, and the weight distribution became more skewed. The BMI curve is comparable to that of other populations, except for higher percentiles. This reflects the increasing prevalence of overweight and obesity. Median age at menarche (13.0 years) has not advanced any more over the past 50 years. Median ages at menarche and B2 in girls and G2 or T4 in boys are comparable to other West European estimates, but approximately 10% enter G2/T4 before 9 years of age.Conclusions: The ongoing secular trend in height and weight makes growth charts previously used in Belgium obsolete. New representative charts for growth and pubertal development are introduced. For weight monitoring, it is advised that the now-available BMI growth charts are used.