Automatic control of blood flow rate on the arterial-line side during cardiopulmonary bypass
Automatic control of blood flow rate on the arterial-line side during cardiopulmonary bypass
复制标题
体外循环时动脉侧血流量的自动控制
DOI：
10.1109/embc46164.2021.9629644
复制
发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Tsuji Toshio
中科院分区：
文献类型：
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作者：
Takahashi Hidenobu;Kinoshita Takuya;Soh Zu;Tsuji Toshio
体外循环（CPB）系统的操作需要熟练的技术和经验。术中，灌注师需要间歇性地操纵静脉和动脉管路侧的两个封堵器，以达到所需的血液流速。为了方便封堵器的操作，我们提出了一个自动控制系统的动脉线侧的血液流速的基础上的动态模型，解决了封堵器的操作和血液流速之间的关系在CPB系统。仿真结果表明，该系统能够控制血液流量，即使在模型参数的估计误差。然后，我们在CPB系统中实现了该控制系统，并进行了自动控制动脉线侧血液流量的实验。我们证实，动脉线侧的血液流速可以遵循手动操作的静脉线侧的血液流速。临床相关性-自动血液流速控制系统的心肺转流系统，本文提出的，有助于减轻负担的封堵器操作的灌注。
The operation of the cardiopulmonary bypass (CPB) system requires skilled techniques and experience. Intraoperatively, the perfusionist needs to intermittently manipulate both of the occluders on the venous- and arterial-line sides to achieve the desired blood flow rates. To facilitate the occluder operation, we propose an automatic control system for the arterial-line side blood flow rate based on a dynamic model that addresses the relationship between the occluder operation and blood flow rate in the CPB system. The simulation results demonstrated that the proposed system was able to control the blood flow rate even when the estimation error of the model parameters was presented. Then, we implemented this control system in the CPB system and conducted an experiment to automatically control the arterial-line side blood flow rate. We confirmed that the blood flow rate on the arterial-line side could follow the manually operated venous-line side blood flow rate.Clinical Relevance--- The automatic blood flow rate control system for a cardiopulmonary bypass system, proposed in this paper, contributes to reducing the burden of occluder operation on a perfusionist.