The Effect of Exercise Training on Endothelial Function in Cardiovascular Disease in Humans
The Effect of Exercise Training on Endothelial Function in Cardiovascular Disease in Humans
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DOI：
10.1097/00003677-200410000-00002
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发表时间：
2004-10
影响因子：
5.7
通讯作者：
C. Walther;S. Gielen;R. Hambrecht
中科院分区：
文献类型：
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作者：
C. Walther;S. Gielen;R. Hambrecht
沃尔特，C.，S. GIELEN和R.汉布雷希特。运动训练对人类心血管疾病内皮功能的影响。运动科学版本号：第32卷，第4期，第100页。129-134，2004.血管内皮功能障碍发生在动脉粥样硬化的早期，是对心血管危险因素的反应。内皮功能障碍的发生主要是一氧化氮（NO）生物利用度降低的结果。它代表了心血管事件的独立预测因子，并预测患者的预后。因此，内皮功能已被确定为治疗干预的靶点。有规律的运动训练是一种通过增加NO生物利用度来改善心血管疾病患者内皮功能障碍的非药物选择。
WALTHER, C., S. GIELEN, and R. HAMBRECHT. The effect of exercise training on endothelial function in cardiovascular disease in humans. Exerc. Sport Sci. Rev., Vol. 32, No. 4, pp. 129–134, 2004. Endothelial dysfunction occurs early in atherosclerosis in response to cardiovascular risk factors. The occurrence of endothelial dysfunction is primarily the result of reduced nitric oxide (NO) bioavailabilty. It represents an independent predictor of cardiovascular events and predicts the prognosis of the patient. Therefore, endothelial function has been identified as a target for therapeutic intervention. Regular exercise training is a nonpharmacological option to improve endothelial dysfunction in patients with cardiovascular disease by increasing NO bioavailability.