Clinical characteristics of pneumonia in hospitalized patients with novel influenza A (H1N1) in Korea

Clinical characteristics of pneumonia in hospitalized patients with novel influenza A (H1N1) in Korea
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DOI:
10.3109/00365540903490026
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发表时间:
2010-04-01
影响因子:
--
通讯作者:
Koh, Yoinsuck
Koh, Yoinsuck
中科院分区:
其他
文献类型:
--
作者:
Choi, Wook Jin;Kim, Won Young;Koh, Yoinsuck

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2009年3月,一种新型H1N1流感病毒(2009 H1N1)出现并在全球范围内传播。我们描述了2009年8月至2009年10月中旬韩国2009年H1N1住院患者的肺炎临床过程。在351名确诊的2009年H1N1感染患者中,共有17名肺炎患者入住急诊室。超过一半的患者年龄在7 - 23岁之间,只有2例患者年龄在65岁或以上。仅6例患者(35.3%)存在基础疾病。17名患者中有10名患者入院时拍摄的胸片显示肺炎伴双侧浸润。尽管进行了密集的复苏努力,但1名患有严重低氧血症的成人患者在急诊科3周后死亡。然而,我们能够在5天内使大多数患者出院,没有任何其他并发症。2009年H1N1是韩国之前健康的学龄人士入院时出现肺炎伴轻度低氧血症的原因。
In March 2009, a novel influenza H1N1 virus (2009 H1N1) emerged and spread worldwide. We describe the clinical course of pneumonia in patients hospitalized with 2009 H1N1 in Korea from August to mid-October 2009. Of 351 patients with a confirmed 2009 H1N1 infection, a total of 17 patients with pneumonia were admitted to an acute care unit. More than half of the patients were between 7 and 23 y of age, and only 2 patients were 65 y of age or older. Only 6 patients (35.3%) had underlying medical conditions. For 10 of the 17 patients, chest radiographs taken on admission had findings of pneumonia with bilateral infiltrates. Despite intensive resuscitative efforts, 1 adult patient arriving with severe hypoxemia in the emergency department died 3 weeks later. However, we were able to discharge most of the patients without any other complication in 5 days. 2009 H1N1 was the cause of pneumonia with mild hypoxemia at admission in previously healthy school-aged persons in Korea.