Predicting health related quality of life 6 months after stroke: the role of anxiety and upper limb dysfunction
Predicting health related quality of life 6 months after stroke: the role of anxiety and upper limb dysfunction
复制标题
DOI：
10.3109/09638288.2012.691942
复制
发表时间：
2013-01-01
影响因子：
2.2
通讯作者：
Donaghy, Marie
中科院分区：
文献类型：
--
作者：
Morris, Jacqui H.;van Wijck, Frederike;Donaghy, Marie
目的：本研究探讨了焦虑和上肢功能障碍等变量作为中风后 6 个月健康相关生活质量 (HRQOL) 预测因素的作用。方法：参与者：之前参加过物理治疗干预随机对照试验的中风幸存者 (n = 85)。因变量：HRQOL - 诺丁汉健康档案 (NHP)。预测变量：情绪 - 医院抑郁和焦虑量表；上肢功能——动作研究手臂测试； Rivermead 运动评估；日常生活活动——修正巴塞尔指数；临床和人口因素。结果：焦虑和抑郁显着预测总体 HRQOL 的 49% 方差（p < 0.05），但只有焦虑显着预测 NHP 疼痛（13% 方差，p < 0.001）、情绪反应（41% 方差，p < 0.001）、睡眠（19% 方差，p = 0.02）和社会孤立（23% 方差，p = 0.02）。抑郁和焦虑共同显着预测能量水平的 30% 差异 (p < 0.001)。 UL 运动障碍和日常生活活动预测 NHP 体力活动评分有 36% 的方差 (p < 0.001)。结论：这项研究表明，在评估焦虑时，它在确定 HRQOL 方面似乎比抑郁更重要。 UL 损伤和 ADL 独立性可预测感知的身体活动。中风发作后很长时间内的焦虑管理策略和 UL 恢复治疗可能有利于感知 HRQOL。
Purpose: This study examined the role of anxiety and upper limb dysfunction, amongst other variables, as predictors of health related quality of life (HRQOL) 6 months after stroke. Method: Participants: Stroke survivors (n = 85) who had previously participated in a randomised controlled trial of a physiotherapy intervention. Dependent variable: HRQOL - Nottingham Health Profile (NHP). Predictor variables: Mood - Hospital Depression and Anxiety Scale; Upper Limb Functioning - Action Research Arm Test; Rivermead Motor Assessment; Activities of Daily Living - Modified Barthel Index; Clinical and demographic factors. Results: Anxiety and depression significantly predicted 49% of variance in overall HRQOL (p < 0.05), but only anxiety significantly predicted NHP pain (13% variance, p < 0.001), emotional reactions (41% variance, p < 0.001), sleep (19% variance, p = 0.02) and social isolation (23% variance, p = 0.02). Depression and anxiety together significantly predicted 30% variance in energy level (p < 0.001). UL motor impairment and activities of daily living predicted 36% of variance in NHP physical activity score (p < 0.001). Conclusions: This study indicates that where anxiety is assessed, it appears more important in determining HRQOL than depression. UL impairment and ADL independence predicted perceived physical activity. Management strategies for anxiety and therapy for UL recovery long after stroke onset are likely to benefit perceived HRQOL.