Prospective Investigation of the Impact of Cannabis Use Disorders on Posttraumatic Stress Disorder Symptoms Among Veterans in Residential Treatment
Prospective Investigation of the Impact of Cannabis Use Disorders on Posttraumatic Stress Disorder Symptoms Among Veterans in Residential Treatment
复制标题
DOI：
10.1037/a0026621
复制
发表时间：
2013-03-01
影响因子：
6.3
通讯作者：
Drescher, Kent D.
中科院分区：
文献类型：
--
作者：
Bonn-Miller, Marcel O.;Boden, Matthew Tyler;Drescher, Kent D.
这项调查旨在提供第一个前瞻性检查的存在下，目前的大麻使用障碍（CUD）诊断和创伤后应激障碍（PTSD）症状的变化之间的关联随着时间的推移，在考虑了年龄，创伤严重程度，心理困扰和共同发生的物质使用障碍的理论相关影响后，停药。该研究是纵向的，在两个时间点评估临床患者：住院PTSD治疗的摄入和出院。样本包括260名男性战斗暴露的退伍军人患者（M-年龄= 52.57岁，SD = 5.47），在2000年至2008年期间接受了退伍军人事务部的创伤后应激障碍住宅康复计划。使用DSM-IV的结构化临床访谈获得诊断，并通过PTSD检查表军事版确定PTSD结局。结果表明，CUD诊断的存在显著预测了PTSD症状严重程度以及PTSD回避麻木和过度觉醒症状群严重程度的较低水平的变化（在治疗开始和出院之间）（所有ps <0.05）。这项研究提出了有问题的大麻使用和PTSD症状之间的前瞻性关系的第一个证据，表明随着时间的推移，患有CUD的个体可能会经历较低水平的PTSD症状变化，在由于住宅PTSD治疗而中断的背景下。
This investigation sought to provide the first prospective examination of the association between the presence of a current cannabis use disorder (CUD) diagnosis and changes in posttraumatic stress disorder (PTSD) symptoms over time after discontinuation, after accounting for the theoretically relevant effects of age, trauma severity, psychological distress, and co-occurring substance use disorders. The study was longitudinal and assessed clinical patients at two time points: residential PTSD treatment intake and discharge. The sample consisted of 260 male combat-exposed military veteran patients (M-age = 52.57 years, SD = 5.47) admitted to a Veterans Affairs residential rehabilitation program for PTSD between 2000 and 2008. Diagnoses were obtained using the Structured Clinical Interview for DSM-IV, and PTSD outcomes were determined by the PTSD Checklist-Military Version. Results indicate that the presence of a CUD diagnosis was significantly predictive of lower levels of change (between treatment intake and discharge) in PTSD symptom severity as well as PTSD avoidance-numbing and hyperarousal symptom cluster severity (all ps < .05). This study presents the first evidence of a prospective relation between problematic cannabis use and PTSD symptoms, indicating that individuals with a CUD are likely to experience lower levels of change in PTSD symptoms over time, within the context of discontinuation owing to residential PTSD treatment.