The Ethology Application of Zebrafish in Neuroscience
The Ethology Application of Zebrafish in Neuroscience
复制标题
斑马鱼行为学在神经科学中的应用
DOI：
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发表时间：
2009
影响因子：
0.3
通讯作者：
Zou, S.-Q.
中科院分区：
文献类型：
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作者：
Hu, B.;Yin, W.;Chen, L.;Yang, Y.-P.;Zou, S.-Q.
斑马鱼作为一种新型动物模型，因其独特的特性而逐渐被人们所接受并广泛应用于生物学研究中。除了在开发研究中使用方便外，在动物行为学中的应用也越来越广泛。由于斑马鱼在受精后2天前透明，眼睛大小接近大脑的一半，并且具有明显的昼夜节律，因此在视觉研究中得到了显著的应用。嗅觉和听觉器官在表面上都是可见的，这种结构使得通过行为实验很容易检测到嗅觉和听觉功能。由于斑马鱼的倾向是活跃的，观察运动非常方便。它在社会生物学的研究中也得到越来越多的应用。斑马鱼行为测试是一种简单有效的分析体内综合神经元功能的方法，目前已经建立了一些实验模型，现将其综述如下。
Zebrafish, as a new model of animal, has been gradually accepted and widely used in biology research due to its special characteristics. Besides its convenience used in development research, the application in ethology is more and more extensively. Because of the transparency before 2 days post-fertilization, the eye size nearly half of the brain and its conspicuous circadian rhythm, zebrafish has been significantly applied in vision research. The organs of olfactory and auditory are both visible on the surface, such structure makes it very easy to detect the olfactory and auditory function by means of behavior experiments. Observation of motion is very convenience as zebrafish's propensity is active. It is also used more and more in social biology research. The behavior test of zebrafish is a simple and effective method to analyze the integrative neuronal function in vivo while some experimental models have been established which reviewed as follows.